EPHB2

Across TCGA cell cohorts, EPHB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,241 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EPHB2-associated GO terms across cancer lineages are Hindbrain tangential cell migration, Postsynaptic membrane assembly, and Integrin-mediated signaling pathway. Each is linked with EPHB2 in more than 16 cancer types. Because this analysis shows association rather than direction, both EPHB2-to-partner and partner-to-EPHB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hindbrain tangential cell migration grouped by EPHB2-low versus EPHB2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHB2→partner) and Y-score (partner→EPHB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Hindbrain tangential cell migration →	+1.489	+2.294	<.001	<.001	3	17
LARGE_INTESTINE	Postsynaptic membrane assembly →	+1.217	+2.051	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Integrin-mediated signaling pathway →	+0.174	+1.853	.001	.008	3	15
STOMACH	Regulation of postsynapse organization →	+0.068	+2.940	<.001	<.001	3	14
BREAST	Regulation of fibroblast proliferation →	+0.111	+2.155	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Positive regulation of myoblast fusion →	+0.176	+1.090	<.001	.006	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,241 associations by consensus.

Hindbrain tangential cell migration by EPHB2 expression — SOFT_TISSUE

Explore this box plot interactively →