EPHA7

Across TCGA patient cohorts, EPHA7 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,642 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPHA7-associated proteins across cancer lineages are PLAU, PKP4, and PLIN3. Each is linked with EPHA7 in more than 5 cancer types. Because this analysis shows association rather than direction, both EPHA7-to-partner and partner-to-EPHA7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHA7 versus PLAU in COAD, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA7→partner) and Y-score (partner→EPHA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PLAU →	-0.713	-0.854	.001	<.001	3	6
UCEC	PKP4 →	+0.499	+1.688	<.001	<.001	3	5
GBM	PLIN3 →	-0.328	-0.959	.006	.003	3	4
HNSC	PML_S480 →	-0.786	-1.411	<.001	<.001	3	4
LSCC	PXN →	-0.453	-1.577	<.001	<.001	3	4
LUAD	SERPINB1 →	-0.505	-1.063	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,642 associations by consensus.

EPHA7 vs PLAU — COAD

Explore this scatter interactively →