EPHA7

Across TCGA patient cohorts, EPHA7 protein abundance is significantly associated with the RNA expression of many other genes, with 7,406 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPHA7-associated genes across cancer lineages are COG4, MAPK10, and CISD1. Each is linked with EPHA7 in more than 2 cancer types. Because this analysis shows association rather than direction, both EPHA7-to-partner and partner-to-EPHA7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHA7 versus COG4 in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA7→partner) and Y-score (partner→EPHA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	COG4 →	+0.764	+2.418	.002	<.001	3	2
GBM	MAPK10 →	+0.593	+0.670	<.001	<.001	3	2
GBM	CISD1 →	+0.368	+0.588	.001	.003	3	2
GBM	OARD1 →	+0.541	+0.933	<.001	<.001	3	2
GBM	APOBEC2 →	+0.745	+1.061	<.001	.001	3	2
CCRCC	KLHDC10 →	+0.423	+0.883	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,406 associations by consensus.

EPHA7 vs COG4 — LSCC

Explore this scatter interactively →