EPHA4

Across TCGA patient cohorts, EPHA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,412 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EPHA4-associated proteins across cancer lineages are RNASE4, RPL12, and IMMT. Each is linked with EPHA4 in more than 3 cancer types. Because this analysis shows association rather than direction, both EPHA4-to-partner and partner-to-EPHA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHA4 versus RNASE4 in BRCA, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA4→partner) and Y-score (partner→EPHA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNASE4 →	+0.552	+0.804	<.001	.001	3	4
GBM	RPL12 →	-0.184	-0.694	.001	.003	3	4
BRCA	IMMT →	-0.305	-0.963	<.001	<.001	3	4
PDAC	SEPTIN4 →	+0.584	+0.957	<.001	<.001	3	4
PDAC	SRRM2_S876 →	-0.291	-0.789	.002	.001	3	4
UCEC	STXBP1 →	+0.532	+0.901	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,412 associations by consensus.

EPHA4 vs RNASE4 — BRCA

Explore this scatter interactively →