EPHA4

Across TCGA cell cohorts, EPHA4 RNA expression is significantly associated with the RNA expression of many other genes, with 8,916 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EPHA4-associated genes across cancer lineages are LBH, RGL1, and NCOA1. Each is linked with EPHA4 in more than 9 cancer types. Because this analysis shows association rather than direction, both EPHA4-to-partner and partner-to-EPHA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHA4 versus LBH in LARGE_INTESTINE, with a Pearson correlation of 0.45.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA4→partner) and Y-score (partner→EPHA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LBH →	+2.862	+1.936	<.001	<.001	3	10
BONE	RGL1 →	+1.949	+2.276	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	NCOA1 →	+1.085	+1.753	<.001	<.001	3	6
STOMACH	KLF12 →	+1.262	+2.008	<.001	.001	2	6
LUNG_NSCLC_LUSC	ZFYVE1 →	+1.004	+1.475	<.001	.001	2	6
BONE	FOXO6 →	+1.737	+2.155	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,916 associations by consensus.

EPHA4 vs LBH — LARGE_INTESTINE

Explore this scatter interactively →