EPHA3

Across TCGA patient cohorts, EPHA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,379 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EPHA3-associated proteins across cancer lineages are ILK, KANK2, and PARVA. Each is linked with EPHA3 in more than 9 cancer types. Because this analysis shows association rather than direction, both EPHA3-to-partner and partner-to-EPHA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHA3 versus ILK in UCEC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA3→partner) and Y-score (partner→EPHA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ILK →	+0.574	+0.972	<.001	<.001	3	10
UCEC	KANK2 →	+0.644	+1.195	<.001	<.001	3	10
UCEC	PARVA →	+0.569	+1.153	<.001	<.001	3	10
OV	SORBS3 →	+0.626	+1.156	<.001	<.001	3	9
UCEC	RSU1 →	+0.491	+1.173	<.001	<.001	3	9
UCEC	C11orf96 →	+0.669	+1.074	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,379 associations by consensus.

EPHA3 vs ILK — UCEC

Explore this scatter interactively →