EPHA3

Across TCGA cell cohorts, EPHA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,354 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EPHA3-associated GO terms across cancer lineages are Cerebral cortex tangential migration, Positive regulation of sodium ion transport, and Neuroblast differentiation. Each is linked with EPHA3 in more than 7 cancer types. Because this analysis shows association rather than direction, both EPHA3-to-partner and partner-to-EPHA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cerebral cortex tangential migration grouped by EPHA3-low versus EPHA3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA3→partner) and Y-score (partner→EPHA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cerebral cortex tangential migration →	+1.096	+1.365	<.001	<.001	3	8
BONE	Positive regulation of sodium ion transport →	-0.168	-1.980	.005	.006	3	6
BONE	Neuroblast differentiation →	+1.410	+2.631	.001	<.001	3	6
OVARY	Negative regulation of endodermal cell differentiation →	+1.174	+0.975	<.001	.009	3	6
BONE	Regulation of smooth muscle cell proliferation →	-0.066	-1.863	.003	.002	3	6
SKIN	Protein localization to cilium →	+0.047	+2.012	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,354 associations by consensus.

Cerebral cortex tangential migration by EPHA3 expression — STOMACH

Explore this box plot interactively →