Across TCGA patient cohorts, EPHA10 mutation is significantly associated with the RNA expression of many other genes, with 3,795 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPHA10-associated genes across cancer lineages are KCTD9, ERCC6L, and NUDCD2. Each is linked with EPHA10 in more than 3 cancer types. Because this analysis shows association rather than direction, both EPHA10-to-partner and partner-to-EPHA10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA10→partner) and Y-score (partner→EPHA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KCTD9 →	+0.539	+2.269	<.001	<.001	3	4
UCEC	ERCC6L →	+0.489	+1.378	.001	.008	3	4
UCEC	NUDCD2 →	+0.323	+1.695	.008	.006	3	4
UCEC	UHRF1 →	+0.814	+2.258	<.001	<.001	3	3
UCEC	BUB3 →	+0.361	+1.981	.001	.007	3	3
UCEC	EME1 →	+0.462	+1.595	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,795 associations by consensus.

Exploration

EPHA10 survival (RNA) · tumor vs normal (RNA) · all EPHA10 data types