Across TCGA cell cohorts, EPHA10 mutation is significantly associated with the RNA expression of many other genes, with 567 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EPHA10-associated genes across cancer lineages are OR14A2, CENPM, and ACBD5. Each is linked with EPHA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both EPHA10-to-partner and partner-to-EPHA10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA10→partner) and Y-score (partner→EPHA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR14A2 →	+0.061	+3.700	<.001	.005	3	2
LARGE_INTESTINE	CENPM →	+0.766	+3.169	<.001	.009	3	2
LARGE_INTESTINE	ACBD5 →	+0.667	+2.628	.006	.002	3	2
LARGE_INTESTINE	NUP88 →	+0.606	+3.321	<.001	.003	3	2
LARGE_INTESTINE	BARD1 →	+0.629	+3.169	.001	.009	3	2
LARGE_INTESTINE	PRIMPOL →	+0.628	+2.628	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 567 associations by consensus.

Exploration

EPHA10 survival (RNA) · tumor vs normal (RNA) · all EPHA10 data types