EPHA1

Across TCGA patient cohorts, EPHA1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,602 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EPHA1-associated genes across cancer lineages are AKT3-IT1, CAMK4, and ABI3BP. Each is linked with EPHA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both EPHA1-to-partner and partner-to-EPHA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHA1 versus AKT3-IT1 in HNSC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA1→partner) and Y-score (partner→EPHA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AKT3-IT1 →	-1.188	-0.386	<.001	<.001	3	3
COAD	CAMK4 →	-0.712	-0.807	.003	.004	2	4
COAD	ABI3BP →	-1.570	-0.990	.001	.008	3	3
HNSC	TTN →	-1.292	-0.306	.005	<.001	3	3
HNSC	KLF5 →	+1.132	+0.408	.001	<.001	3	3
HNSC	WASL →	+0.426	+0.280	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,602 associations by consensus.

EPHA1 vs AKT3-IT1 — HNSC

Explore this scatter interactively →