EPHA1

Across TCGA cell cohorts, EPHA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,875 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible EPHA1-associated GO terms across cancer lineages are Regulation of protein import into nucleus, Cell junction assembly, and Establishment or maintenance of apical/basal cell polarity. Each is linked with EPHA1 in more than 12 cancer types. Because this analysis shows association rather than direction, both EPHA1-to-partner and partner-to-EPHA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein import into nucleus grouped by EPHA1-low versus EPHA1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA1→partner) and Y-score (partner→EPHA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of protein import into nucleus →	+0.105	+1.620	<.001	<.001	3	13
OESOPHAGUS	Cell junction assembly →	+0.081	+1.819	.001	.004	3	13
OESOPHAGUS	Establishment or maintenance of apical/basal cell polarity →	+0.123	+1.816	.003	.005	3	13
OESOPHAGUS	Establishment or maintenance of bipolar cell polarity →	+0.123	+1.816	.003	.005	3	13
OVARY	T cell mediated cytotoxicity →	+0.235	+2.542	<.001	<.001	3	12
PANCREAS	Protein localization to cell surface →	+0.129	+2.521	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,875 associations by consensus.

Regulation of protein import into nucleus by EPHA1 expression — PANCREAS

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