EPG5

Across TCGA patient cohorts, EPG5 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,888 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EPG5-associated proteins across cancer lineages are SMAD4, TXNL1, and RPL3. Each is linked with EPG5 in more than 6 cancer types. Because this analysis shows association rather than direction, both EPG5-to-partner and partner-to-EPG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPG5 versus SMAD4 in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPG5→partner) and Y-score (partner→EPG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMAD4 →	+0.262	+0.341	<.001	<.001	3	7
LSCC	TXNL1 →	+0.353	+0.491	<.001	<.001	3	5
BRCA	RPL3 →	-0.398	-0.552	<.001	.001	3	5
BRCA	RPL4 →	-0.414	-0.615	<.001	<.001	3	5
OV	RPL7A →	-0.442	-1.197	<.001	<.001	3	5
GBM	MBD1 →	+0.246	+0.226	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,888 associations by consensus.

EPG5 vs SMAD4 — LSCC

Explore this scatter interactively →