EPG5

Across TCGA patient cohorts, EPG5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,552 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EPG5-associated genes across cancer lineages are LMAN1, PIK3C3, and NOP53. Each is linked with EPG5 in more than 3 cancer types. Because this analysis shows association rather than direction, both EPG5-to-partner and partner-to-EPG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPG5 versus LMAN1 in LUAD, with a Pearson correlation of 0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPG5→partner) and Y-score (partner→EPG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LMAN1 →	+0.372	+0.160	.006	.006	3	4
BRCA	PIK3C3 →	+0.374	+0.184	<.001	<.001	3	3
LUAD	NOP53 →	-0.446	-0.161	<.001	.004	3	3
PDAC	MISP3 →	-0.618	-0.200	<.001	.004	3	3
BRCA	C18orf25 →	+0.526	+0.213	<.001	<.001	3	3
PDAC	SPRYD3 →	-0.244	-0.212	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,552 associations by consensus.

EPG5 vs LMAN1 — LUAD

Explore this scatter interactively →