EPG5

Across TCGA patient cohorts, EPG5 mutation is significantly associated with the RNA expression of many other genes, with 6,514 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPG5-associated genes across cancer lineages are KIR2DL4, CENPM, and NKG7. Each is linked with EPG5 in more than 4 cancer types. Because this analysis shows association rather than direction, both EPG5-to-partner and partner-to-EPG5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIR2DL4 grouped by EPG5-low versus EPG5-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPG5→partner) and Y-score (partner→EPG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	KIR2DL4 →	+0.662	+2.606	.001	<.001	3	5
STAD	CENPM →	+0.834	+3.459	.001	.005	3	4
UCEC	NKG7 →	+1.106	+1.683	<.001	<.001	3	4
UCEC	TPI1 →	+0.420	+1.793	<.001	<.001	3	4
BRCA	GNLY →	+1.021	+3.584	.003	.003	3	4
UCEC	EXOSC9 →	+0.383	+1.693	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,514 associations by consensus.

KIR2DL4 by EPG5 expression — BLCA

Explore this box plot interactively →