EPC1

Across TCGA patient cohorts, EPC1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,379 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPC1-associated genes across cancer lineages are USP6NL, TAF5, and DCLRE1C. Each is linked with EPC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both EPC1-to-partner and partner-to-EPC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPC1 versus USP6NL in LSCC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPC1→partner) and Y-score (partner→EPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	USP6NL →	+0.770	+0.278	<.001	<.001	3	4
BRCA	TAF5 →	+0.458	+0.269	.001	<.001	3	4
BRCA	DCLRE1C →	+0.498	+0.298	<.001	<.001	3	4
BRCA	RPP38 →	+0.501	+0.309	<.001	<.001	3	4
LSCC	MTPAP →	+0.595	+0.286	<.001	<.001	3	3
UCEC	CCNY →	+0.320	+0.150	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,379 associations by consensus.

EPC1 vs USP6NL — LSCC

Explore this scatter interactively →