EPB41L4A

Across TCGA patient cohorts, EPB41L4A protein abundance is significantly associated with the RNA expression of many other genes, with 3,742 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EPB41L4A-associated genes across cancer lineages are EPB41L4A-DT, MTFR2, and HASPIN. Each is linked with EPB41L4A in more than 3 cancer types. Because this analysis shows association rather than direction, both EPB41L4A-to-partner and partner-to-EPB41L4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPB41L4A versus EPB41L4A-DT in BRCA, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L4A→partner) and Y-score (partner→EPB41L4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EPB41L4A-DT →	+0.673	+0.592	<.001	<.001	3	4
OV	MTFR2 →	-0.983	-0.588	<.001	<.001	3	3
LUAD	HASPIN →	-0.779	-0.451	<.001	<.001	3	3
BRCA	AGR3 →	+4.054	+0.800	<.001	<.001	3	3
BRCA	C9orf152 →	+1.553	+0.411	<.001	<.001	3	3
HNSC	LRGUK →	+0.766	+1.472	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,742 associations by consensus.

EPB41L4A vs EPB41L4A-DT — BRCA

Explore this scatter interactively →