EPB41L4A

Across TCGA cell cohorts, EPB41L4A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,478 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPB41L4A-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Protein destabilization, and Negative regulation of autophagy. Each is linked with EPB41L4A in more than 9 cancer types. Because this analysis shows association rather than direction, both EPB41L4A-to-partner and partner-to-EPB41L4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by EPB41L4A-low versus EPB41L4A-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L4A→partner) and Y-score (partner→EPB41L4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of myoblast fusion →	+0.109	+1.550	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein destabilization →	+0.094	+1.594	<.001	<.001	3	9
OVARY	Negative regulation of autophagy →	+0.055	+1.443	.004	<.001	3	9
OVARY	Regulation of myoblast fusion →	+0.105	+1.460	<.001	<.001	3	9
BLOOD_Leukemia	Macroautophagy →	+0.037	+0.548	<.001	.006	3	9
STOMACH	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.049	+0.911	.002	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,478 associations by consensus.

Negative regulation of myoblast fusion by EPB41L4A expression — OVARY

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