EPB41L4A

Across TCGA cell cohorts, EPB41L4A mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPB41L4A-associated genes across cancer lineages are SLC32A1, MT4, and G6PC2. Each is linked with EPB41L4A in more than 1 cancer types. Because this analysis shows association rather than direction, both EPB41L4A-to-partner and partner-to-EPB41L4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC32A1 grouped by EPB41L4A-low versus EPB41L4A-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L4A→partner) and Y-score (partner→EPB41L4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SLC32A1 →	+0.065	+4.315	<.001	.006	3	1
CNS	MT4 →	+0.177	+4.321	<.001	.009	3	1
CNS	G6PC2 →	+0.014	+4.472	.009	.004	3	1
BLOOD_Leukemia	MYL7 →	+0.057	+3.339	<.001	.006	3	1
BLOOD_Leukemia	KCNF1 →	+0.408	+4.009	<.001	.002	3	1
BLOOD_Leukemia	C8orf74 →	+0.026	+3.567	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

SLC32A1 by EPB41L4A expression — CNS

Explore this box plot interactively →