EPB41L2

Across TCGA patient cohorts, EPB41L2 protein abundance is significantly associated with the protein abundance of many other proteins, with 27,275 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EPB41L2-associated proteins across cancer lineages are EPB41L2_S715, EPB41L2_S499, and EPB41L2_S550. Each is linked with EPB41L2 in more than 9 cancer types. Because this analysis shows association rather than direction, both EPB41L2-to-partner and partner-to-EPB41L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPB41L2 versus EPB41L2_S715 in UCEC, with a Pearson correlation of 0.84.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L2→partner) and Y-score (partner→EPB41L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EPB41L2_S715 →	+0.987	+0.826	<.001	<.001	3	10
OV	EPB41L2_S499 →	+0.788	+0.397	<.001	.004	2	10
OV	EPB41L2_S550 →	+0.920	+0.661	.004	.002	2	10
UCEC	EPB41L2_S828 →	+1.330	+0.777	<.001	<.001	3	9
HNSC	EPB41L2_S87 →	+0.953	+0.622	<.001	<.001	3	9
HNSC	APPL1 →	+0.302	+0.401	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 27,275 associations by consensus.

EPB41L2 vs EPB41L2_S715 — UCEC

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