EPB41L2

Across TCGA cell cohorts, EPB41L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,381 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible EPB41L2-associated GO terms across cancer lineages are Regulation of chromosome segregation, Regulation of metaphase/anaphase transition of cell cycle, and Regulation of mitotic metaphase/anaphase transition. Each is linked with EPB41L2 in more than 12 cancer types. Because this analysis shows association rather than direction, both EPB41L2-to-partner and partner-to-EPB41L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome segregation grouped by EPB41L2-low versus EPB41L2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L2→partner) and Y-score (partner→EPB41L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of chromosome segregation →	+0.111	+1.916	<.001	.001	3	13
SKIN	Regulation of metaphase/anaphase transition of cell cycle →	+0.088	+1.370	<.001	.001	3	12
BREAST	Regulation of mitotic metaphase/anaphase transition →	+0.110	+1.700	<.001	.006	3	12
KIDNEY	Mitotic spindle elongation →	+0.268	+1.292	<.001	<.001	3	11
KIDNEY	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.144	+1.145	.005	<.001	3	11
KIDNEY	Negative regulation of chromosome separation →	+0.144	+1.145	.005	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,381 associations by consensus.

Regulation of chromosome segregation by EPB41L2 expression — BREAST

Explore this box plot interactively →