EPB41L1

Across TCGA patient cohorts, EPB41L1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,260 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EPB41L1-associated genes across cancer lineages are RAPGEFL1, FKBP11, and DEFB1. Each is linked with EPB41L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both EPB41L1-to-partner and partner-to-EPB41L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPB41L1 versus RAPGEFL1 in HNSC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L1→partner) and Y-score (partner→EPB41L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RAPGEFL1 →	+1.184	+0.590	<.001	<.001	3	6
OV	FKBP11 →	-0.773	-0.878	<.001	<.001	3	6
OV	DEFB1 →	+2.144	+0.603	.001	.001	3	6
CCRCC	ASPG →	+1.397	+0.288	<.001	<.001	3	6
COAD	BASP1 →	-1.171	-0.624	<.001	<.001	3	6
COAD	MUC20 →	+1.109	+0.552	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,260 associations by consensus.

EPB41L1 vs RAPGEFL1 — HNSC

Explore this scatter interactively →