EPB41L1

Across TCGA cell cohorts, EPB41L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,791 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EPB41L1-associated GO terms across cancer lineages are Regulation of protein localization to membrane, Negative regulation of protein-containing complex assembly, and Vacuolar transport. Each is linked with EPB41L1 in more than 11 cancer types. Because this analysis shows association rather than direction, both EPB41L1-to-partner and partner-to-EPB41L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to membrane grouped by EPB41L1-low versus EPB41L1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L1→partner) and Y-score (partner→EPB41L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of protein localization to membrane →	+0.088	+1.091	<.001	<.001	3	12
BREAST	Negative regulation of protein-containing complex assembly →	+0.081	+1.997	<.001	<.001	2	12
OVARY	Vacuolar transport →	+0.053	+1.504	.004	.002	3	11
BONE	Response to epidermal growth factor →	+0.115	+0.864	.002	.005	3	11
BONE	Hormone-mediated signaling pathway →	+0.095	+1.154	<.001	.001	3	11
BONE	Positive regulation of protein localization to cell periphery →	+0.100	+1.056	.001	.002	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,791 associations by consensus.

Regulation of protein localization to membrane by EPB41L1 expression — BONE

Explore this box plot interactively →