EPB41

Across TCGA patient cohorts, EPB41 protein abundance is significantly associated with the RNA expression of many other genes, with 4,050 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EPB41-associated genes across cancer lineages are HBB, PF4, and HBA2. Each is linked with EPB41 in more than 7 cancer types. Because this analysis shows association rather than direction, both EPB41-to-partner and partner-to-EPB41 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPB41 versus HBB in PDAC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41→partner) and Y-score (partner→EPB41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HBB →	+2.241	+0.341	<.001	<.001	3	8
GBM	PF4 →	+1.053	+0.663	<.001	<.001	3	7
GBM	HBA2 →	+1.969	+0.831	<.001	<.001	3	7
GBM	HBA1 →	+1.828	+0.789	<.001	<.001	3	7
OV	FOSB →	+2.098	+0.492	.003	.002	3	6
GBM	ALAS2 →	+0.708	+0.654	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,050 associations by consensus.

EPB41 vs HBB — PDAC

Explore this scatter interactively →