EPB41

Across TCGA cell cohorts, EPB41 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,197 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EPB41-associated GO terms across cancer lineages are Extracellular structure organization, Regulation of coagulation, and Extracellular matrix organization. Each is linked with EPB41 in more than 17 cancer types. Because this analysis shows association rather than direction, both EPB41-to-partner and partner-to-EPB41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Extracellular structure organization grouped by EPB41-low versus EPB41-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41→partner) and Y-score (partner→EPB41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Extracellular structure organization →	-0.197	-2.843	<.001	<.001	3	18
BONE	Regulation of coagulation →	-0.223	-2.946	<.001	<.001	3	17
BONE	Extracellular matrix organization →	-0.197	-2.843	<.001	<.001	3	17
BONE	External encapsulating structure organization →	-0.197	-2.524	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Regulation of hemostasis →	-0.207	-1.120	.004	.003	3	16
LUNG_NSCLC_LUSC	Regulation of blood coagulation →	-0.207	-1.120	.003	.003	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,197 associations by consensus.

Extracellular structure organization by EPB41 expression — BONE

Explore this box plot interactively →