EP400P1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EP400P1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EP400P1-associated genes across cancer lineages are AVP, ANKRD63, and PRAMEF7. Each is linked with EP400P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EP400P1-to-partner and partner-to-EP400P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EP400P1→partner) and Y-score (partner→EP400P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEAVP →+0.048+3.217<.001.00631
LARGE_INTESTINEANKRD63 →+0.272+3.478<.001.00531
BLOOD_LeukemiaPRAMEF7 →+0.012+5.539.001.00331
LARGE_INTESTINEFAM170A →+0.105+3.070<.001.00921
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration