Across TCGA patient cohorts, EP400 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,077 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EP400-associated proteins across cancer lineages are SART3, SRSF9, and NONO. Each is linked with EP400 in more than 5 cancer types. Because this analysis shows association rather than direction, both EP400-to-partner and partner-to-EP400 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EP400→partner) and Y-score (partner→EP400) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SART3 →	+0.209	+0.442	.001	.002	3	6
GBM	SRSF9 →	+0.424	+0.699	<.001	<.001	3	6
GBM	NONO →	+0.149	+0.346	<.001	<.001	3	5
GBM	NUP133 →	+0.187	+0.382	<.001	.007	3	5
GBM	DHX9 →	+0.218	+0.542	<.001	<.001	3	5
GBM	PNN →	+0.352	+0.521	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,077 associations by consensus.

Exploration

EP400 survival (RNA) · tumor vs normal (RNA) · all EP400 data types