EOMES

Across TCGA patient cohorts, EOMES RNA expression is significantly associated with the protein abundance of many other proteins, with 14,528 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EOMES-associated proteins across cancer lineages are ARHGAP45, PLEK, and PSMB10. Each is linked with EOMES in more than 9 cancer types. Because this analysis shows association rather than direction, both EOMES-to-partner and partner-to-EOMES results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EOMES versus ARHGAP45 in OV, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EOMES→partner) and Y-score (partner→EOMES) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARHGAP45 →	+0.596	+0.912	<.001	<.001	3	10
UCEC	PLEK →	+0.673	+0.917	<.001	<.001	3	10
UCEC	PSMB10 →	+0.689	+0.997	<.001	<.001	3	10
GBM	PTPN7 →	+0.641	+0.591	<.001	<.001	3	10
OV	RAC2 →	+0.950	+1.064	<.001	<.001	3	10
GBM	RASAL3 →	+0.591	+0.819	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,528 associations by consensus.

EOMES vs ARHGAP45 — OV

Explore this scatter interactively →