EOMES

Across TCGA patient cohorts, EOMES protein abundance is significantly associated with the protein abundance of many other proteins, with 4,360 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EOMES-associated proteins across cancer lineages are CD8A, DOCK2, and ALOX5AP. Each is linked with EOMES in more than 2 cancer types. Because this analysis shows association rather than direction, both EOMES-to-partner and partner-to-EOMES results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EOMES versus CD8A in CCRCC, with a Pearson correlation of 0.79.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EOMES→partner) and Y-score (partner→EOMES) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CD8A →	+1.254	+0.660	<.001	<.001	3	3
HNSC	DOCK2 →	+0.628	+0.629	.005	<.001	2	3
CCRCC	ALOX5AP →	+1.112	+0.975	<.001	<.001	3	2
HNSC	RNF213_S39 →	+0.776	+0.466	.001	.003	3	2
BRCA	ACTR2_T117 →	+0.421	+0.858	<.001	<.001	3	2
CCRCC	CSNK2A1 →	-0.327	-0.545	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,360 associations by consensus.

EOMES vs CD8A — CCRCC

Explore this scatter interactively →