EOMES

Across TCGA cell cohorts, EOMES RNA expression is significantly associated with the go_rna of many other GO terms, with 3,379 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EOMES-associated GO terms across cancer lineages are snRNA processing, Regulation of microtubule-based process, and DNA-templated transcription initiation. Each is linked with EOMES in more than 8 cancer types. Because this analysis shows association rather than direction, both EOMES-to-partner and partner-to-EOMES results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snRNA processing grouped by EOMES-low versus EOMES-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EOMES→partner) and Y-score (partner→EOMES) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	snRNA processing →	+0.062	+0.707	.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of microtubule-based process →	+0.055	+0.454	<.001	<.001	3	8
OESOPHAGUS	DNA-templated transcription initiation →	+0.065	+0.793	<.001	<.001	3	8
OESOPHAGUS	Regulation of centrosome cycle →	+0.086	+0.769	.002	.001	2	9
BREAST	Protein localization to nucleus →	+0.036	+0.345	.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA replication →	+0.054	+0.265	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,379 associations by consensus.

snRNA processing by EOMES expression — OESOPHAGUS

Explore this box plot interactively →