EOLA1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, EOLA1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated EOLA1 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher EOLA1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated EOLA1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

SARC and UCEC are the cancer types where EOLA1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SARCDFSMedianAll0.1210.611.0416view →
UCECDFSMedianAll1.0000.629.0256view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration