EOGT

Across TCGA pan-cancer cohorts, EOGT mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated EOGT data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher EOGT mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated EOGT expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

LSCC, LUAD, and PDAC are the cancer types where EOGT mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.550	0.926	<.001	44	view →
LUAD	DFS	Median	II,III,IV	0.252	0.805	.019	9	view →
PDAC	OS	Median	All	0.783	0.899	.011	9	view →
CCRCC	DFS	Tertile	All	0.608	0.853	.009	8	view →
HNSC	DFS	Median	II,III,IV	0.985	0.907	.044	4	view →
GBM	DFS	Tertile	All	0.264	0.440	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

EOGT–LSCC (OS)

Open the LSCC breakdown →