EOGT

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EOGT protein abundance is significantly associated with the RNA expression of many other genes, with 13,757 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EOGT-associated genes across cancer lineages are DSE, POSTN, and TGFBI. Each is linked with EOGT in more than 6 cancer types. Because this analysis shows association rather than direction, both EOGT-to-partner and partner-to-EOGT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EOGT versus DSE in LSCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EOGT→partner) and Y-score (partner→EOGT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCDSE →+0.905+0.342<.001<.00137
GBMPOSTN →+3.501+0.393<.001.00237
GBMTGFBI →+1.516+0.369<.001<.00136
OVCTHRC1 →+1.701+0.497<.001<.00136
OVCLMP →+1.161+0.501<.001<.00136
OVHAS2 →+1.124+0.466<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,757 associations by consensus.

EOGT vs DSE — LSCC

Per-sample scatter of EOGT vs DSE in LSCC (Pearson r = 0.52).

Explore this scatter interactively →

Exploration