EOGT

Across TCGA cell cohorts, EOGT mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EOGT-associated genes across cancer lineages are SOST, CXorf51A, and IL2. Each is linked with EOGT in more than 1 cancer types. Because this analysis shows association rather than direction, both EOGT-to-partner and partner-to-EOGT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SOST grouped by EOGT-low versus EOGT-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EOGT→partner) and Y-score (partner→EOGT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SOST →	+0.495	+3.643	<.001	.005	3	1
SKIN	CXorf51A →	+0.258	+2.925	.008	.007	3	1
BLOOD_Leukemia	IL2 →	+0.982	+4.276	<.001	.007	3	1
BLOOD_Leukemia	SLC17A4 →	+0.079	+4.152	<.001	.009	3	1
BLOOD_Leukemia	CER1 →	+0.984	+4.152	<.001	.009	3	1
BLOOD_Leukemia	OR4K2 →	+0.031	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

SOST by EOGT expression — SKIN

Explore this box plot interactively →