ENY2

Across TCGA pan-cancer cohorts, ENY2 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ENY2 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ENY2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ENY2 expression acts as an unfavorable survival marker, although some lineages such as COAD and GBM show a favorable association.

COAD, HNSC, and GBM are the cancer types where ENY2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.886	.019	60	view →
HNSC	DFS	Median	IV	0.328	0.889	.014	24	view →
GBM	OS	Tertile	All	0.515	0.304	.022	12	view →
LSCC	OS	Median	All	1.000	0.938	.013	12	view →
LUAD	DFS	Tertile	III,IV	0.774	0.264	.019	11	view →
CCRCC	DFS	Quartile	III,IV	0.424	0.869	.026	9	view →
PDAC	OS	Median	All	0.947	0.703	.004	7	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ENY2–COAD (DFS)

Open the COAD breakdown →