Across TCGA patient cohorts, ENTPD8 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENTPD8-associated genes across cancer lineages are ER-alpha, Annexin-1, and p53. Each is linked with ENTPD8 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTPD8-to-partner and partner-to-ENTPD8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD8→partner) and Y-score (partner→ENTPD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ER-alpha →	+0.918	+2.820	.026	.035	3	1
UCEC	Annexin-1 →	+0.650	+2.321	.013	.035	3	1
SKCM	p53 →	+0.281	+2.824	.013	.036	3	1
UCEC	ERK2 →	+0.242	+2.321	.012	.035	2	1
UCEC	Chk2_pT68 →	-0.194	-2.321	.038	.035	2	1
UCEC	Syk →	+0.474	+2.335	.011	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

ENTPD8 survival (RNA) · tumor vs normal (RNA) · all ENTPD8 data types