Across TCGA patient cohorts, ENTPD6 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENTPD6-associated genes across cancer lineages are ERK2, Ku80, and PDK1_pS241. Each is linked with ENTPD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTPD6-to-partner and partner-to-ENTPD6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD6→partner) and Y-score (partner→ENTPD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.173	+3.459	.012	.005	3	2
UCEC	Ku80 →	+0.200	+1.939	.018	.003	3	2
UCEC	PDK1_pS241 →	+0.150	+1.807	.014	.025	3	2
UCEC	14-3-3_beta →	-0.100	-1.571	.005	.019	3	1
UCEC	EGFR_pY1068 →	-0.238	-1.925	.008	.005	3	1
UCEC	EGFR →	-0.173	-2.558	.002	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

ENTPD6 survival (RNA) · tumor vs normal (RNA) · all ENTPD6 data types