Across TCGA cell cohorts, ENTPD6 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ENTPD6-associated genes across cancer lineages are TLX3, CLPS, and OR56B1. Each is linked with ENTPD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTPD6-to-partner and partner-to-ENTPD6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD6→partner) and Y-score (partner→ENTPD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TLX3 →	+0.016	+4.867	<.001	.009	3	1
LUNG_NSCLC_LUAD	CLPS →	+0.087	+5.662	.008	.002	3	1
LUNG_NSCLC_LUAD	OR56B1 →	+0.048	+4.887	<.001	.009	3	1
BLOOD_Leukemia	GUCA2A →	+0.052	+5.969	<.001	.001	3	1
BLOOD_Leukemia	KRTAP7-1 →	+0.095	+5.539	<.001	.003	3	1
LARGE_INTESTINE	OR4L1 →	+0.014	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

ENTPD6 survival (RNA) · tumor vs normal (RNA) · all ENTPD6 data types