Across TCGA patient cohorts, ENTPD5 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENTPD5-associated genes across cancer lineages are A-Raf_pS299, GAPDH, and P-Cadherin. Each is linked with ENTPD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTPD5-to-partner and partner-to-ENTPD5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD5→partner) and Y-score (partner→ENTPD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.121	-3.000	.029	.036	3	1
UCEC	GAPDH →	+0.690	+3.459	.005	.005	3	1
UCEC	P-Cadherin →	-0.219	-3.169	.001	.018	3	1
UCEC	Rab25 →	-0.376	-3.169	.015	.019	3	1
UCEC	Annexin_VII →	-0.148	-2.584	.022	.011	3	1
UCEC	Tuberin →	+0.360	+2.584	.004	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

ENTPD5 survival (RNA) · tumor vs normal (RNA) · all ENTPD5 data types