Across TCGA patient cohorts, ENTPD4 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENTPD4-associated genes across cancer lineages are 4E-BP1, Annexin-1, and Caspase-7-cleavedD198. Each is linked with ENTPD4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ENTPD4-to-partner and partner-to-ENTPD4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD4→partner) and Y-score (partner→ENTPD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.299	+1.807	.007	.027	3	3
UCEC	Annexin-1 →	+0.749	+3.341	<.001	.005	3	2
UCEC	Caspase-7-cleavedD198 →	+0.664	+2.341	.006	.019	3	2
UCEC	14-3-3_beta →	-0.089	-3.143	.032	.018	3	1
UCEC	EGFR →	-0.193	-3.169	.003	.019	3	1
UCEC	A-Raf_pS299 →	-0.196	-2.459	<.001	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

ENTPD4 survival (RNA) · tumor vs normal (RNA) · all ENTPD4 data types