ENTPD2

Across TCGA cell cohorts, ENTPD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,062 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ENTPD2-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, Negative regulation of inflammatory response to wounding, and Bundle of His cell to Purkinje myocyte communication. Each is linked with ENTPD2 in more than 11 cancer types. Because this analysis shows association rather than direction, both ENTPD2-to-partner and partner-to-ENTPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of epithelial cell apical/basal polarity grouped by ENTPD2-low versus ENTPD2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD2→partner) and Y-score (partner→ENTPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Establishment of epithelial cell apical/basal polarity →	-0.201	-1.175	<.001	<.001	3	12
URINARY_TRACT	Negative regulation of inflammatory response to wounding →	+0.182	+1.040	<.001	.002	2	10
LIVER	Bundle of His cell to Purkinje myocyte communication →	+0.280	+2.141	<.001	<.001	3	9
STOMACH	Serotonin secretion →	+1.144	+1.700	<.001	<.001	3	9
PANCREAS	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.094	+1.279	<.001	<.001	3	9
BREAST	Positive regulation of regulated secretory pathway →	+0.093	+2.061	.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,062 associations by consensus.

Establishment of epithelial cell apical/basal polarity by ENTPD2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →