ENTPD2

Across TCGA cell cohorts, ENTPD2 mutation is significantly associated with the RNA expression of many other genes, with 491 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ENTPD2-associated genes across cancer lineages are CNIH1, MED31, and RFC5. Each is linked with ENTPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTPD2-to-partner and partner-to-ENTPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CNIH1 grouped by ENTPD2-low versus ENTPD2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD2→partner) and Y-score (partner→ENTPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CNIH1 →	+0.432	+2.588	.005	.004	3	2
LARGE_INTESTINE	MED31 →	+0.825	+3.628	<.001	<.001	3	2
LARGE_INTESTINE	RFC5 →	+0.521	+2.502	.005	.005	3	2
LARGE_INTESTINE	TTC33 →	+0.709	+2.502	<.001	.005	3	2
LARGE_INTESTINE	ZNF644 →	+0.472	+2.502	<.001	.005	3	2
LARGE_INTESTINE	SRP9 →	+0.378	+3.237	.009	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 491 associations by consensus.

CNIH1 by ENTPD2 expression — LARGE_INTESTINE

Explore this box plot interactively →