ENTPD1

Across TCGA patient cohorts, ENTPD1 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENTPD1-associated genes across cancer lineages are Cyclin-B1, Caspase-8, and FoxM1. Each is linked with ENTPD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ENTPD1-to-partner and partner-to-ENTPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by ENTPD1-low versus ENTPD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD1→partner) and Y-score (partner→ENTPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.602	+1.807	.001	.004	3	3
UCEC	Caspase-8 →	-0.291	-2.523	<.001	<.001	3	2
UCEC	FoxM1 →	+0.232	+1.916	.008	.009	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.414	-1.584	.006	.034	3	2
SKCM	NF-kB-p65_pS536 →	-0.493	-3.321	.015	.010	3	1
UCEC	EGFR_pY1068 →	-0.170	-1.514	.047	.015	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Cyclin-B1 by ENTPD1 expression — UCEC

Explore this box plot interactively →