ENTPD1

Across TCGA cell cohorts, ENTPD1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ENTPD1-associated genes across cancer lineages are LCE1F, OR1L3, and PNLIPRP1. Each is linked with ENTPD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTPD1-to-partner and partner-to-ENTPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE1F grouped by ENTPD1-low versus ENTPD1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD1→partner) and Y-score (partner→ENTPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LCE1F →	+0.122	+4.415	<.001	.007	3	1
OVARY	OR1L3 →	+0.036	+4.029	<.001	.009	3	1
OVARY	PNLIPRP1 →	+0.029	+4.450	<.001	.004	3	1
OVARY	IFNA17 →	+0.015	+4.807	<.001	.003	3	1
BLOOD_Leukemia	OR11H1 →	+0.097	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR4K2 →	+0.042	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

LCE1F by ENTPD1 expression — LARGE_INTESTINE

Explore this box plot interactively →