Across TCGA pan-cancer cohorts, ENSAP1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of ENSAP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where ENSAP1 RNA is repressed in tumor relative to normal tissue. In most cancer types ENSAP1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC are the cancer types where ENSAP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ENSAP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	−0.150	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: ENSAP1 RNA expression & survival · all ENSAP1 data types