ENPP7P4

Across TCGA pan-cancer cohorts, ENPP7P4 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ENPP7P4 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher ENPP7P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ENPP7P4 expression acts as an unfavorable survival marker, although some lineages such as CESC and HNSC show a favorable association.

LIHC, ACC, and CESC are the cancer types where ENPP7P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	II,III,IV	0.473	0.724	<.001	64	view →
ACC	DFS	Median	All	0.282	0.624	<.001	56	view →
CESC	DFS	Tertile	IV	0.690	0.173	<.001	44	view →
HNSC	OS	Median	IV	0.501	0.323	.007	29	view →
PRAD	DFS	Tertile	All	0.836	0.941	.001	24	view →
READ	OS	Tertile	III,IV	0.878	0.621	.010	21	view →
PAAD	OS	Median	II,III,IV	0.554	0.324	.018	17	view →
UCEC	OS	Median	All	0.837	0.904	.010	14	view →
LGG	OS	Tertile	All	0.938	0.826	<.001	13	view →
THYM	DFS	Median	III,IV	1.000	0.480	.010	13	view →
LUSC	DFS	Median	II,III,IV	0.631	0.840	.017	7	view →
KICH	DFS	Quartile	All	0.705	1.000	.013	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ENPP7P4–LIHC (OS)

Open the LIHC breakdown →