ENPP7P3

Across TCGA pan-cancer cohorts, ENPP7P3 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated ENPP7P3 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ENPP7P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ENPP7P3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and THYM show a favorable association.

KICH, ACC, and SKCM are the cancer types where ENPP7P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	II,III,IV	0.328	0.894	<.001	138	view →
ACC	DFS	Tertile	All	0.046	0.753	<.001	66	view →
SKCM	DFS	Tertile	All	0.893	0.724	.004	24	view →
ESCA	OS	Tertile	All	0.574	0.742	.012	24	view →
STAD	OS	Quartile	III,IV	0.434	0.671	.014	18	view →
LIHC	OS	Tertile	All	0.255	0.773	.012	18	view →
LUSC	OS	Tertile	II,III,IV	0.331	0.627	.015	18	view →
PCPG	DFS	Tertile	All	0.418	0.855	.017	15	view →
COAD	DFS	Tertile	IV	0.028	0.496	<.001	9	view →
TGCT	DFS	Tertile	All	0.360	0.730	.026	6	view →
SARC	OS	Tertile	All	0.190	0.531	.006	6	view →
THYM	DFS	Tertile	All	1.000	0.718	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

ENPP7P3–KICH (DFS)

Open the KICH breakdown →