ENPP7

Across TCGA patient cohorts, ENPP7 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,218 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ENPP7-associated proteins across cancer lineages are METAP1, GRB2, and SP140_S291. Each is linked with ENPP7 in more than 3 cancer types. Because this analysis shows association rather than direction, both ENPP7-to-partner and partner-to-ENPP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENPP7 versus METAP1 in LSCC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPP7→partner) and Y-score (partner→ENPP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	METAP1 →	-0.277	-0.269	<.001	<.001	3	4
LUAD	GRB2 →	+0.247	+0.210	<.001	<.001	3	4
UCEC	SP140_S291 →	+1.055	+0.343	<.001	.001	3	4
HNSC	INPP5D_S243 →	+0.540	+0.493	<.001	.005	3	4
HNSC	MZB1 →	+0.650	+0.301	.001	<.001	3	3
LSCC	PLCG2 →	+0.539	+0.275	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,218 associations by consensus.

ENPP7 vs METAP1 — LSCC

Explore this scatter interactively →