ENPP5

Across TCGA cell cohorts, ENPP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,593 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ENPP5-associated GO terms across cancer lineages are Vesicle budding from membrane, Adenylate cyclase-activating G protein-coupled receptor signaling pathway, and Adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Each is linked with ENPP5 in more than 13 cancer types. Because this analysis shows association rather than direction, both ENPP5-to-partner and partner-to-ENPP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle budding from membrane grouped by ENPP5-low versus ENPP5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPP5→partner) and Y-score (partner→ENPP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Vesicle budding from membrane →	+0.073	+1.302	<.001	.002	3	14
KIDNEY	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.072	-1.096	<.001	<.001	3	14
KIDNEY	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.061	-0.881	<.001	.001	3	13
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.100	+1.284	<.001	.004	2	14
URINARY_TRACT	Vesicle coating →	+0.127	+1.976	<.001	<.001	3	13
URINARY_TRACT	Vesicle targeting, rough ER to cis-Golgi →	+0.115	+1.724	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,593 associations by consensus.

Vesicle budding from membrane by ENPP5 expression — STOMACH

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