ENPP3

Across TCGA patient cohorts, ENPP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,500 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ENPP3-associated proteins across cancer lineages are TMC5_S184, POLR3G_S157, and VWA5A. Each is linked with ENPP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ENPP3-to-partner and partner-to-ENPP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENPP3 versus TMC5_S184 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPP3→partner) and Y-score (partner→ENPP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMC5_S184 →	+1.766	+1.581	<.001	<.001	3	4
BRCA	POLR3G_S157 →	-1.261	-1.524	.001	<.001	3	4
BRCA	VWA5A →	+0.740	+1.790	<.001	<.001	3	4
CCRCC	BBS2 →	+0.232	+1.140	.004	.002	3	4
COAD	AMACR →	+1.086	+1.929	<.001	<.001	3	4
BRCA	KRT8_S457 →	+1.329	+1.094	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,500 associations by consensus.

ENPP3 vs TMC5_S184 — BRCA

Explore this scatter interactively →