ENPP2

Across TCGA cell cohorts, ENPP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,346 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ENPP2-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Golgi vesicle transport. Each is linked with ENPP2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ENPP2-to-partner and partner-to-ENPP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by ENPP2-low versus ENPP2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPP2→partner) and Y-score (partner→ENPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of myoblast fusion →	+0.104	+0.089	<.001	.005	3	8
STOMACH	Negative regulation of myoblast fusion →	+0.126	+2.708	.001	.001	3	8
PANCREAS	Golgi vesicle transport →	+0.073	+0.123	<.001	<.001	3	8
PANCREAS	Regulation of syncytium formation by plasma membrane fusion →	+0.115	+0.124	<.001	<.001	3	8
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.111	+2.029	<.001	<.001	3	8
SKIN	Response to hydrostatic pressure →	+0.145	+2.544	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,346 associations by consensus.

Regulation of myoblast fusion by ENPP2 expression — PANCREAS

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